Publications

  1. Bauer T., Trump S., Ishaque N., Thurmann L., Gu L., Bauer M., Bieg M., Gu Z. G., Weichenhan D., Mallm J. P., et al: Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Molecular Systems Biology 2016, 12:18. (Impact-Faktor 2020: 11,429)
  2. Bender S., Gronych J., Warnatz H. J., Hutter B., Grobner S., Ryzhova M., Pfaff E., Hovestadt V., Weinberg F., Halbach S., et al: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma. Nature Medicine 2016, 22:1314-1320. (Impact-Faktor 2020: 53,440)
  3. Dubash T. D., Hoffmann C. M., Oppel F., Giessler K. M., Weber S., Dieter S. M., Hüllein J., Zenz T., Herbst F., Scholl C., et al: Phenotypic differentiation does not affect tumorigenicity of primary human colon cancer initiating cells. Cancer Letters 2016, 371:326-333. (Impact-Faktor 2020: 8,679)
  4. Evers C., Kaufmann L., Seitz A., Paramasivam N., Granzow M., Karch S., Fischer C., Hinderhofer K., Gdynia G. P., Elsässer M., et al: Exome sequencing reveals a novel CWF19L1 mutation associated with intellectual disability and cerebellar atrophy. American Journal of Medical Genetics Part A 2016, 170:1502 - 1509. (Impact-Faktor 2020: 2,802)
  5. Gröschel S., Bommer M., Hutter B., Budczies J., Bonekamp D., Heining C., Horak P., Fröhlich M., Uhrig S., Hübschmann D., et al: Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification. Cold Spring Harbor Molecular Case Studies 2016, 2:a001180. (Impact-Faktor 2020: nn)
  6. Hartmann L., Dutta S., Opatz S., Vosberg S., Reiter K., Leubolt G., Metzeler K. H., Herold T., Bamopoulos S. A., Braeundl K., et al: ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation. Nature Communications 2016, 7. (Impact-Faktor 2020: 14,919)
  7. Hutter S., Piro R. M., Waszak S. M., Kehrer-Sawatzki H., Friedrich R. E., Lassaletta A., Witt O., Korbel J. O., Lichter P., Schuhmann M. U., et al: No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients. Human Genetics 2016, 135:469-475. (Impact-Faktor 2020: 4,132)
  8. Johann P. D., Erkek S., Zapatka M., Kerl K., Buchhalter I., Hovestadt V., Jones D. T. W., Sturm D., Hermann C., Wang M. S., et al: Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell 2016, 29:379-393. (Impact-Faktor 2020: 31,743)
  9. Kordes M., Roring M., Heining C., Braun S., Hutter B., Richter D., Georg C., Scholl C., Groschel S., Roth W., et al: Cooperation of BRAF(F595L) and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling. Leukemia 2016, 30:937-946. (Impact-Faktor 2020: 11,528)
  10. Lin C. Y., Erkek S., Tong Y., Yin L., Federation A. J., Zapatka M., Haldipur P., Kawauchi D., Risch T., Warnatz H. J., et al: Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature 2016, 530:57-62. (Impact-Faktor 2020: 49,962)
  11. Noll E. M., Eisen C., Stenzinger A., Espinet E., Muckenhuber A., Klein C., Vogel V., Klaus B., Nadler W., Rösli C., et al: CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma. Nature Medicine 2016, 22:278-287. (Impact-Faktor 2020: 53,440)
  12. Oakes C. C., Seifert M., Assenov Y., Gu L., Przekopowitz M., Ruppert A. S., Wang Q., Imbusch C. D., Serva A., Koser S. D., et al: DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia. Nature Genetics 2016, 48:253-264. (Impact-Faktor 2020: 38,330)
  13. Pickl J. M. A., Tichy D., Kuryshev V. Y., Tolstov Y., Falkenstein M., Schüler J., Reidenbach D., Hotz-Wagenblatt A., Kristiansen G., Roth W., et al: Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression. Oncotarget 2016, 7:59589-59603. (Impact-Faktor 2020: 2016: 5,168)
  14. Rafiullah R., Aslamkhan M., Paramasivam N., Thiel C., Mustafa G., Wiemann S., Schlesner M., Wade R. C., Rappold G. A., Berkel S.: Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family. Journal of Medical Genetics 2016, 53:138-144. (Impact-Faktor 2020: 6,318)
  15. Sahm F., Schrimpf D., Jones D. T., Meyer J., Kratz A., Reuss D., Capper D., Koelsche C., Korshunov A., Wiestler B., et al: Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets. Acta Neuropatholgica 2016, 131:903-910. (Impact-Faktor 2020: 17,088)
  16. Salvermoser M., Chotewutmontri S., Braspenning-Wesch I., Hasche D., Rosl F., Vinzon S. E.: Transcriptome analysis of Mastomys natalensis papillomavirus in productive lesions after natural infection. Journal of General Virology 2016, 97:1658-1669. (Impact-Faktor 2020: 3,891)
  17. Sturm D., Orr B. A., Toprak U. H., Hovestadt V., Jones D. T. W., Capper D., Sill M., Buchhalter I., Northcott P. A., Leis I., et al: New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. Cell 2016, 164:1060-1072. (Impact-Faktor 2020: 41,582)
  18. Trump S., Bieg M., Gu Z. G., Thurmann L., Bauer T., Bauer M., Ishaque N., Roder S., Gu L., Herberth G., et al: Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation. Scientific Reports 2016, 6. (Impact-Faktor 2020: 4,379)
  19. Wang Q., Satomi K., Oh J. E., Hutter B., Brors B., Diessl N., Liu H.-K., Wolf S., Wiestler O., Kleihues P., et al: Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea. American Journal of Pathology 2016, 186:2569-2576. (Impact-Faktor 2020: 4,307)
  20. Wollny D., Zhao S., Everlien I., Lun X., Brunken J., Brüne D., Ziebell F., Tabansky I., Weichert W., Marciniak-Czochra A., Martin-Villalba A.: Single-Cell Analysis Uncovers Clonal Acinar Cell Heterogeneity in the Adult Pancreas. Developmental Cell 2016, 39:289-301. (Impact-Faktor 2020: 12,270)
  21. Worst B. C., van Tilburg C. M., Balasubramanian G. P., Fiesel P., Witt R., Freitag A., Boudalil M., Previti C., Wolf S., Schmidt S., et al: Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study. European Journal of Cancer 2016, 65:91-101. (Impact-Faktor 2020: 9,162)
  22. Agaimy A., Bieg M., Michal M., Geddert H., Märkl B., Seitz J., Moskalev E. A., Schlesner M., Metzler M., Hartmann A., et al: Recurrent Somatic PDGFRB Mutations in Sporadic Infantile/Solitary Adult Myofibromas But Not in Angioleiomyomas and Myopericytomas. American Journal of Surgical Pathology 2017, 41:195-203. (Impact-Faktor 2020: 6,394)
  23. Ball C. R., Oppel F., Ehrenberg K. R., Dubash T. D., Dieter S. M., Hoffmann C. M., Abel U., Herbst F., Koch M., Werner J., et al: Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts. EMBO Molecular Medicine 2017, 9:918-932. (Impact-Faktor 2020: 12,137)
  24. Böhm J., Pianka F., Stüttgen N., Rho J., Gigic B., Zhang Y., Habermann N., Schrotz-King P., Abbenhardt-Martin C., Zielske L., et al: Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study. Surgery 2017, 161:808 - 817. (Impact-Faktor 2020: 3,982)
  25. Bott A., Erdem N., Lerrer S., Hotz-Wagenblatt A., Breunig C., Abnaof K., Wörner A., Wilhelm H., Münstermann E., Ben-Baruch A., Wiemann S.: miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A. Oncotarget 2017, 8:43897-43914. (Impact-Faktor 2020: 2016: 5,168)
  26. Brocks D., Schmidt C. R., Daskalakis M., Jang H. S., Shah N. M., Li D., Li J., Zhang B., Hou Y., Laudato S., et al: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats. Nature Genetics 2017, 49:1052-1060. (Impact-Faktor 2020: 38,330)
  27. Chudasama P., Renner M., Straub M., Mughal S. S., Hutter B., Kosaloglu Z., Schwessinger R., Scheffler M., Alldinger I., Schimmack S., et al: Targeting Fibroblast Growth Factor Receptor 1 for Treatment of Soft-Tissue Sarcoma. Clinical Cancer Research 2017, 23:962-973. (Impact-Faktor 2020: 12,531)
  28. Delacher M., Imbusch C. D., Weichenhan D., Breiling A., Hotz-Wagenblatt A., Träger U., Hofer A. C., Kägebein D., Wang Q., Frauhammer F., et al: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues. Nature Immunology 2017, 18:1160-1172. (Impact-Faktor 2020: 25,606)
  29. Dieter S. M., Heining C., Agaimy A., Huebschmann D., Bonekamp D., Hutter B., Ehrenberg K. R., Froehlich M., Schlesner M., Scholl C., et al: Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma. Annals of Oncology 2017, 28:142-148. (Impact-Faktor 2020: 32,976)
  30. Dikow N., Granzow M., Graul-Neumann L. M., Karch S., Hinderhofer K., Paramasivam N., Behl L. J., Kaufmann L., Fischer C., Evers C., et al: DDX3X mutations in two girls with a phenotype overlapping Toriello-Carey syndrome. American Journal of Medical Genetics Part A 2017, 173:1369-1373. (Impact-Faktor 2020: 2,802)
  31. Doering K., Ahmed N., Riemer T., Suresh H. G., Vainshtein Y., Habich M., Riemer J., Mayer M. P., O'Brien E. P., Kramer G., Bukau B.: Profiling Ssb-Nascent Chain Interactions Reveals Principles of Hsp70-Assisted Folding. Cell 2017, 170:298-+. (Impact-Faktor 2020: 41,582)
  32. Evers C., Staufner C., Granzow M., Paramasivam N., Hinderhofer K., Kaufmann L., Fischer C., Thiel C., Opladen T., Kotzaeridou U., et al: Impact of clinical exomes in neurodevelopmental and neurometabolic disorders. Molecular Genetics and Metabolism 2017, 121:297-307. (Impact-Faktor 2020: 4,797)
  33. Giessler K. M., Kleinheinz K., Huebschmann D., Balasubramanian G. P., Dubash T. D., Dieter S. M., Siegl C., Herbst F., Weber S., Hoffmann C. M., et al: Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer. Journal of Experimental Medicine 2017, 214:2073-2087. (Impact-Faktor 2020: 14,307)
  34. Haderk F., Schulz R., Iskar M., Cid L. L., Worst T., Willmund K. V., Schulz A., Warnken U., Seiler J., Benner A., et al: Tumor-derived exosomes modulate PD-L1 expression in monocytes. Science Immunology 2017, 2. (Impact-Faktor 2020: 17,727)
  35. Heilmann K., Toth R., Bossmann C., Klimo K., Plass C., Gerhauser C.: Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer. Oncogene 2017, 36:6446-6461. (Impact-Faktor 2020: 9,867)
  36. Hettmer S., Andrieux G., Hochrein J., Kurz P., Rössler J., Lassmann S., Werner M., von Bubnoff N., Peters C., Koscielniak E., et al: Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents. Pediatric Blood & Cancer 2017, 64. (Impact-Faktor 2020: 3,167)
  37. Horak P., Klink B., Heining C., Groschel S., Hutter B., Frohlich M., Uhrig S., Hubschmann D., Schlesner M., Eils R., et al: Precision oncology based on omics data: The NCT Heidelberg experience. International Journal of Cancer 2017, 141:877-886. (Impact-Faktor 2020: 7,396)
  38. Jabs J., Zickgraf F. M., Park J., Wagner S., Jiang X., Jechow K., Kleinheinz K., Toprak U. H., Schneider M. A., Meister M., et al: Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations. Molecular Systems Biology 2017, 13. (Impact-Faktor 2020: 11,429)
  39. Jaekel C., Bergmann F., Toth R., Assenov Y., van der Duin D., Strobel O., Hank T., Kloeppel G., Dorrell C., Grompe M., et al: Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability. Nature Communications 2017, 8. (Impact-Faktor 2020: 14,919)
  40. Lipka D. B., Witte T., Toth R., Yang J., Wiesenfarth M., Noellke P., Fischer A., Brocks D., Gu Z., Park J., et al: RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia. Nature Communications 2017, 8. (Impact-Faktor 2020: 14,919)
  41. Mamlouk S., Childs L. H., Aust D., Heim D., Melching F., Oliveira C., Wolf T., Durek P., Schumacher D., Blaeker H., et al: DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer. Nature Communications 2017, 8. (Impact-Faktor 2020: 14,919)
  42. Northcott P. A., Buchhalter I., Morrissy A. S., Hovestadt V., Weischenfeldt J., Ehrenberger T., Groebner S., Segura-Wang M., Zichner T., Rudneva V. A., et al: The whole-genome landscape of medulloblastoma subtypes. Nature 2017, 547:311-+. (Impact-Faktor 2020: 49,962)
  43. Paramasivam N., Granzow M., Evers C. M., Hinderhofer K., Wiemann S., Bartram C. R., Eils R., Schlesner M.: Identification and prioritisation of causal variants in human genetic disorders from exome or whole genome sequencing data. bioRxiv 2017. (Impact-Faktor 2020: nn)
  44. Pei W. K., Feyerabend T. B., Rossler J., Wang X., Postrach D., Busch K., Rode I., Klapproth K., Dietlein N., Quedenau C., et al: Polylox barcoding reveals haematopoietic stem cell fates realized in vivo. Nature 2017, 548:456-+. (Impact-Faktor 2020: 49,962)
  45. Rafiullah R., Long A. B., Ivanova A. A., Ali H., Berkel S., Mustafa G., Paramasivam N., Schlesner M., Wiemann S., Wade R. C., et al: A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity. European Journal of Human Genetics 2017, 25:1324-1334. (Impact-Faktor 2020: 4,246)
  46. Ratnaparkhe M., Hlevnjak M., Kolb T., Jauch A., Maass K. K., Devens F., Rode A., Hovestadt V., Korshunov A., Pastorczak A., et al: Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis. Leukemia 2017, 31:2048-2056. (Impact-Faktor 2020: 11,528)
  47. Ryl T., Kuchen E. E., Bell E., Shao C., Florez A. F., Moenke G., Gogolin S., Friedrich M., Lamprecht F., Westermann F., Hoefer T.: Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug. Cell Systems 2017, 5:237-+. (Impact-Faktor 2020: 10,304)
  48. Sahm F., Toprak U. H., Huebschmann D., Kleinheinz K., Buchhalter I., Sill M., Stichel D., Schick M., Bewerunge-Hudler M., Schrimpf D., et al: Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature. Acta Neuropathologica 2017, 134:155-158. (Impact-Faktor 2020: 17,088)
  49. Scholz S. J., Fronza R., Bartholomä C. C., Cesana D., Montini E., Von Kalle C., Gil-Farina I., Schmidt M.: Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation. Human Gene Therapy 2017, 28:875-885. (Impact-Faktor 2020: 5,695)
  50. Chudasama P., Mughal S. S., Sanders M. A., Huebschmann D., Chung I., Deeg K. I., Wong S.-H., Rabe S., Hlevnjak M., Zapatka M., et al: Integrative genomic and transcriptomic analysis of leiomyosarcoma. Nature Communications 2018, 9. (Impact-Faktor 2020: 14,919)
  51. Dietrich S., Oles M., Lu J. Y., Sellner L., Anders S., Velten B., Wu B., Hullein J., Liberio M. D., Walther T., et al: Drug-perturbation-based stratification of blood cancer. Journal of Clinical Investigation 2018, 128:427-445. (Impact-Faktor 2020: 14,808)
  52. Gerhauser C., Favero F., Risch T., Simon R., Feuerbach L., Assenov Y., Heckmann D., Sidiropoulos N., Waszak S. M., Hübschmann D., et al: Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories. Cancer Cell 2018, 34:996-1011.e1018. (Impact-Faktor 2020: 31,743)
  53. Greif P. A., Hartmann L., Vosberg S., Stief S. M., Mattes R., Hellmann I., Metzeler K. H., Herold T., Bamopoulos S. A., Kerbs P., et al: Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients. Clinical Cancer Research 2018, 24:1716-1726. (Impact-Faktor 2020: 12,531)
  54. Groebner S. N., Worst B. C., Weischenfeldt J., Buchhalter I., Kleinheinz K., Rudneva V. A., Johann P. D., Balasubramanian G. P., Segura-Wang M., Brabetz S., et al: The landscape of genomic alterations across childhood cancers. Nature 2018, 555:321-+. (Impact-Faktor 2020: 49,962)
  55. Gutekunst J., Andriantsoa R., Falckenhayn C., Hanna K., Stein W., Rasamy J., Lyko F.: Clonal genome evolution and rapid invasive spread of the marbled crayfish. Nature Ecology & Evolution 2018, 2:567-573. (Impact-Faktor 2020: 15,460)
  56. Heining C., Horak P., Uhrig S., Codo P. L., Klink B., Hutter B., Fröhlich M., Bonekamp D., Richter D., Steiger K., et al: NRG1 fusions in KRAS wild-type pancreatic cancer. Cancer Discovery 2018, 8:1087-1095. (Impact-Faktor 2020: 39,397)
  57. Hoefflin R., Geißler A. L., Fritsch R., Claus R., Wehrle J., Metzger P., Reiser M., Mehmed L., Fauth L., Heiland D. H., et al: Personalized clinical decision making through implementation of a molecular tumor board: A German single-center experience. JCO Precision Oncology 2018:1-16. (Impact-Faktor 2020: 4,853)
  58. Jethwat A., Slabicki M., Huellein J., Jentzsch M., Dala V., Rabe S., Wagner L., Walther T., Klapper W., Bohnenberger H., et al: TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. Blood 2018, 131:2789-2802. (Impact-Faktor 2020: 22,113)
  59. Kumar A., Bandapalli O. R., Paramasivam N., Giangiobbe S., Diquigiovanni C., Bonora E., Eils R., Schlesner M., Hemminki K., Försti A.: Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family. Scientific Reports 2018, 8. (Impact-Faktor 2020: 4,379)
  60. Li R., Cauchy P., Ramamoorthy S., Boller S., Chavez L., Grosschedl R.: Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. Genes & Development 2018, 32:96-111. (Impact-Faktor 2020: 11,361)
  61. Lier A., Penzel R., Heining C., Horak P., Frohlich M., Uhrig S., Budczies J., Kirchner M., Volckmar A.-L., Hutter B., et al: Validating Comprehensive Next-Generation Sequencing Results for Precision Oncology: The NCT/DKTK Molecularly Aided Stratification for Tumor Eradication Research Experience. JCO Precision Oncology 2018, 2. (Impact-Faktor 2020: 4,853)
  62. Mack S. C., Pajtler K. W., Chavez L., Okonechnikov K., Bertrand K. C., Wang X., Erkek S., Federation A., Song A., Lee C., et al: Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature 2018, 553:101-+. (Impact-Faktor 2020: 49,962)
  63. Pfaff E., Kessler T., Balasubramanian G. P., Berberich A., Schrimpf D., Wick A., Debus J., Unterberg A., Bendszus M., Herold-Mende C., et al: Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation-the NCT Neuro Master Match (N2M2) pilot study. Neuro-Oncology 2018, 20:826-837. (Impact-Faktor 2020: 12,300)
  64. Ratnaparkhe M., Wong J. K. L., Wei P. C., Hlevnjak M., Kolb T., Simovic M., Haag D., Paul Y., Devens F., Northcott P., et al: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors. Nature Communications 2018, 9:13. (Impact-Faktor 2020: 14,919)
  65. Rodríguez-Paredes M., Bormann F., Raddatz G., Gutekunst J., Lucena-Porcel C., Köhler F., Wurzer E., Schmidt K., Gallinat S., Wenck H., et al: Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin. Nature Communications 2018, 9. (Impact-Faktor 2020: 14,919)
  66. Roh V., Abramowski P., Hiou-Feige A., Cornils K., Rivals J.-P., Zougman A., Aranyossy T., Thielecke L., Truan Z., Mermod M., et al: Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma. Cell Reports 2018, 25:2208-+. (Impact-Faktor 2020: 9,423)
  67. Rollenske T., Szijarto V., Lukasiewicz J., Guachalla L. M., Stojkovic K., Hartl K., Stulik L., Kocher S., Lasitschka F., Al-Saeedi M., et al: Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen. Nature Immunology 2018, 19:617-+. (Impact-Faktor 2020: 25,606)
  68. Saatci Ö., Borgoni S., Akbulut Ö., Durmuş S., Raza U., Eyüpoǧlu E., Alkan C., Akyol A., Kütük Ö., Wiemann S., Şahin Ö.: Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer. Oncogene 2018, 37:2251-2269. (Impact-Faktor 2020: 9,867)
  69. Saporito-Magrina C. M., Musacco-Sebio R. N., Andrieux G., Kook L., Orrego M. T., Tuttolomondo M. V., Desimone M. F., Boerries M., Borner C., Repetto M. G.: Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress. Metallomics 2018, 10:13. (Impact-Faktor 2020: 4,526)
  70. Schlereth K., Weichenhan D., Bauer T., Heumann T., Giannakouri E., Lipka D., Jaeger S., Schlesner M., Aloy P., Eils R., et al: The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. eLife 2018, 7. (Impact-Faktor 2020: 8,140)
  71. Simm F., Griesbeck A., Choukair D., Weiß B., Paramasivam N., Klammt J., Schlesner M., Wiemann S., Martinez C., Hoffmann G. F., et al: Identification of SLC20A1 and SLC15A4 among other genes as potential risk factors for combined pituitary hormone deficiency. Genetics in Medicine 2018, 20:728-736. (Impact-Faktor 2020: 8,822)
  72. Viarisio D., Müller-Decker K., Accardi R., Robitaille A., Dürst M., Beer K., Jansen L., Flechtenmacher C., Bozza M., Harbottle R., et al: Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice. PLoS Pathogens 2018, 14. (Impact-Faktor 2020: 6,823)
  73. Waszak S. M., Northcott P. A., Buchhalter I., Robinson G. W., Sutter C., Groebner S., Grund K. B., Brugières L., Jones D. T. W., Pajtler K. W., et al: Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. The Lancet Oncology 2018, 19:785-798. (Impact-Faktor 2020: 41,316)
  74. Weichenhan D., Wang Q., Adey A., Wolf S., Shendure J., Eils R., Plass C.: Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing. Methods in molecular biology 2018, 1708:105-122. (Impact-Faktor 2020: nn)
  75. Aslam M., Ullah A., Paramasivam N., Kandasamy N., Naureen S., Badshah M., Khan K., Wajid M., Abbasi R., Eils R., et al: Segregation and potential functional impact of a rare stop-gain PABPC4L variant in familial atypical Parkinsonism. Scientific Reports 2019, 9. (Impact-Faktor 2020: 4,379)
  76. Bageritz J., Willnow P., Valentini E., Leible S., Boutros M., Teleman A. A.: Gene expression atlas of a developing tissue by single cell expression correlation analysis. Nature Methods 2019, 16:750-756. (Impact-Faktor 2020: 28,547)
  77. Barth J., Abou-El-Ardat K., Dalic D., Kurrle N., Maier A.-M., Mohr S., Schuette J., Vassen L., Greve G., Schulz-Fincke J., et al: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML. Leukemia 2019, 33:1411-1426. (Impact-Faktor 2020: 11,528)
  78. Baser A., Skabkin M., Kleber S., Dang Y., Gülcüler Balta G. S., Kalamakis G., Göpferich M., Ibañez D. C., Schefzik R., Lopez A. S., et al: Onset of differentiation is post-transcriptionally controlled in adult neural stem cells. Nature 2019, 566:100-104. (Impact-Faktor 2020: 49,962)
  79. Beyes S., Andrieux G., Schrempp M., Aicher D., Wenzel J., Antón-García P., Boerries M., Hecht A.: Genome-wide mapping of DNA-binding sites identifies stemness-related genes as directly repressed targets of SNAIL1 in colorectal cancer cells. Oncogene 2019, 38:6647-6661. (Impact-Faktor 2020: 9,867)
  80. Caudron-Herger M., Rusin S. F., Adamo M. E., Seiler J., Schmid V. K., Barreau E., Kettenbach A. N., Diederichs S.: R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. Molecular Cell 2019, 75:184-+. (Impact-Faktor 2020: 17,970)
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